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Related Experiment Videos

Optic disc morphometry in chronic primary open-angle glaucoma. I. Morphometric intrapapillary characteristics.

J B Jonas1, G C Gusek, G O Naumann

  • 1Augenklinik mit Poliklinik, Universität Erlangen-Nürnberg, Federal Republic of Germany.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|January 1, 1988
PubMed
Summary
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Glaucoma alters the neuroretinal rim

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Optic Nerve Head Morphology

Background:

  • Glaucoma is a leading cause of irreversible blindness.
  • Assessing optic nerve head (ONH) morphology is crucial for glaucoma diagnosis.
  • The characteristic shape of the neuroretinal rim in normal eyes is well-established.

Purpose of the Study:

  • To investigate morphometric differences in the optic nerve head between normal subjects and patients with chronic primary open-angle glaucoma.
  • To identify specific changes in the neuroretinal rim configuration associated with early glaucoma.

Main Methods:

  • Morphometric evaluation of 427 optic discs from glaucoma patients and 253 from normal subjects.
  • Comparison of neuroretinal rim area and width across different disc sectors.

Related Experiment Videos

  • Analysis of the cup-to-disc (c/d) ratio.

    • Main Results:

    • Glaucoma significantly alters the neuroretinal rim's configuration compared to normal eyes.
    • Specific changes include decreased rim area in temporal sectors and a pathognomonic smallest rim width outside the horizontal temporal sector.
    • The horizontal to vertical c/d ratio is lowered in glaucomatous eyes.

    Conclusions:

    • Morphometric analysis reveals distinct differences in optic nerve head structure between normal and early glaucomatous eyes.
    • These findings aid in the early detection and diagnosis of glaucoma.
    • Overall optic disc size does not differ significantly and smaller discs are not more susceptible.