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Updated: Dec 27, 2025

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
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Functionalized Microstructured Optical Fibers: Materials, Methods, Applications.

Timur Ermatov1, Julia S Skibina2, Valery V Tuchin3,4,5

  • 1Skolkovo Institute of Science and Technology, 3 Nobelya str., 121205 Moscow, Russia.

Materials (Basel, Switzerland)
|February 26, 2020
PubMed
Summary
This summary is machine-generated.

Microstructured optical fiber sensors offer high sensitivity for analyzing small volumes of low-concentration solutions. This review covers structural modification and surface functionalization techniques for enhanced detection in biophotonics.

Keywords:
functionalizationholey fibershybrid fibersmicrostructured optical fibersmodificationphotonic crystal fiberssensing

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Area of Science:

  • Photonics
  • Biotechnology
  • Medicine

Background:

  • Microstructured optical fiber sensors (MOF) are widely used in photonics, biotechnology, and medicine.
  • Their high sensitivity to refractive index variations makes them ideal for analyzing small volumes and low concentrations.

Purpose of the Study:

  • To review modern techniques for modifying MOF structure to enhance detection sensitivity.
  • To discuss surface functionalization processes for selective molecule adsorption.
  • To highlight potential applications of functionalized MOF sensors in biophotonics.

Main Methods:

  • Review of structural modification techniques for MOFs.
  • Analysis of surface functionalization methods for selective adsorption.
  • Discussion of novel functionalized MOF-based devices.

Main Results:

  • MOF sensors demonstrate high sensitivity for chemical and biochemical analysis.
  • Structural modifications and surface functionalization significantly enhance detection capabilities.
  • Functionalized MOFs show potential for advanced biophotonic applications.

Conclusions:

  • Functionalized MOF sensors offer enhanced detection sensitivity and selectivity.
  • These sensors have broad potential applications in remote sensing, thermography, and disease detection.
  • Further development of functionalized MOFs will advance biophotonics and medical diagnostics.