Consecutive electrocardiographic changes during percutaneous coronary intervention for acute coronary syndrome with
Hiroyuki Sueyoshi1, Yuzo Akita2, Yohei Oishi2
1Division of Cardiology, Osaka Saiseikai Izuo Hospital, 3-4-5 Kitamura, Taisho-ku, Osaka, 551-0032, Japan. men.tan.pin.0708@gmail.com.
Insights
Early percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) with high-grade atrioventricular block (HAVB) improves survival. Prompt reperfusion of blocked arteries can restore heart rhythm and prevent long-term complications.
Area of Science:
- Cardiology
- Interventional Cardiology
- Electrophysiology
Background:
- Acute coronary syndrome (ACS) with high-grade atrioventricular block (HAVB) presents a significant mortality risk.
- Early percutaneous coronary intervention (PCI) in ACS with HAVB is linked to better in-hospital survival rates.
- Survival at six months post-PCI for ACS with HAVB is comparable to ACS cases without HAVB.
Observation:
- A 70-year-old male patient presented with ACS and HAVB, exhibiting complete AV block, complete right bundle branch block (CRBBB), and left axis deviation.
- Coronary angiography revealed severe stenosis in the right coronary artery (RCA) and total occlusion of the proximal left anterior descending artery (LAD).
- Following primary PCI of the RCA and LAD, TIMI grade 3 flow was restored, and the patient's HAVB resolved to normal sinus rhythm within three days.
Findings:
- Early and intensive coronary artery reperfusion in ACS with HAVB leads to favorable long-term survival outcomes.
- The complex blood supply to the AV node and bundle branches means multivessel ischemia can cause severe conduction impairment.
- Successful PCI restored normal conduction, resolving the high-grade atrioventricular block.
Implications:
- This case highlights the importance of prompt PCI in managing ACS with HAVB.
- Understanding the intricate vascular anatomy supplying the conduction system is crucial for interventional cardiologists.
- Timely reperfusion therapy can significantly improve outcomes for patients with complex coronary artery disease and conduction abnormalities.
Background:
Acute coronary syndrome (ACS) with high-grade atrioventricular block (HAVB) still has a poor mortality risk, even in the current percutaneous coronary intervention (PCI) era. However, early PCI for ACS with HAVB is associated with improved in-hospital survival and a 6-month survival similar to that of ACS without HAVB.
Case Presentation:
A 70-year-old man was admitted to our hospital for ACS with HAVB. ECG showed complete AV block, complete right bundle branch block (CRBBB), and left axis deviation. Cardiac enzymes were elevated. He underwent temporary pacemaker insertion and coronary angiography, which showed severe stenosis of the proximal right coronary artery (RCA), 99% stenosis of the distal RCA with Thrombolysis in Myocardial Infarction (TIMI) grade 2 flow, and total occlusion of the proximal left anterior descending artery (LAD). We performed primary PCI in both the RCA and LAD, which resulted in TIMI grade 3 flow in both. After PCI, the HAVB recovered to normal sinus rhythm with CRBBB; a normal QRS interval returned within three days. The patient was discharged from the hospital without complications.
Conclusion:
In this case of ACS with HAVB, early intensive coronary artery reperfusion resulted in long-term patient survival. The blood supply to the AV node and bilateral bundle branches is complex. Multivessel ischemia may compromise both primary and collateral blood flows to the AV node and septum, resulting in severe conduction impairment. Clinicians performing PCI should be aware of this anatomy and physiology.
Related Concept Videos
Dysrhythmias IV: Characteristics of Bradyarrhythmias
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome III: Diagnostic Studies
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias


