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L-657,398, a novel antifungal agent: fermentation, isolation, structural elucidation and biological properties
R E Schwartz1, J Liesch, O Hensens
1Merck Sharp & Dohme Research Laboratories, Rahway, N.J.
The Journal of Antibiotics
|December 1, 1988
Abstract:
L-657,398 is a broad spectrum antifungal agent isolated from solid fermentation or from the mycelium of the liquid fermentation of Aspergillus ochraceus. Structurally, the compound is a novel pyrollidine related to anisomycin.