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Updated: Dec 27, 2025

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments
Published on: May 26, 2019
Operational consistency of medical linear accelerators manufactured and commissioned in series
Callistus M Nguyen1,2, Alan H Baydush2, James D Ververs2
1Biomedical Engineering, Virginia Tech - Wake Forest School of Biomedical Engineering and Sciences, 575 N. Patterson Ave, Winston-Salem, NC 27101, United States.
Abstract:
The purpose of this study was to determine if medical linear accelerators (linac) produced by the same manufacturer exhibit operational consistency within their subsystems and components. Two linacs that were commissioned together and installed at the same facility were monitored. Each machine delivered a daily robust quality assurance (QA) irradiation. Linacs and their components operate consistently, but have different operational parameter levels even when produced by the same manufacturer and commissioned in series. These findings have implications on the feasibility of true clinical beam matching.
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