Related Experiment Video
Updated: Dec 27, 2025

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
Published on: September 28, 2022
[Impact of the Epstein Barr virus on gastric cancer in Peru]
Brady Beltrán Gárate1, Anais Camara2, María Del Carmen Kapsoli Sánchez3
1Departamento Oncología Médica, Radioterapia Hospital Edgardo Rebagliati Martins. Lima, Perú; Centro de Medicina de Precisión, Facultad de Medicina, Universidad de San Martin de Porres. Lima, Perú.
Abstract:
Epstein Barr Virus (EBV) is responsible of 10% of Gastric Cancer (GC), correlating with better survival rates. In Peru, there were not studies about prevalence and clinical characteristics of CG EBV positive.
Objective:
Determine prevalence and clinicopathological characteristics of GC EBV positive.
Materials And Methods:
111 GC tumour samples were centrally screened by Chromogenic in situ hybridization (CISH) technique for EBV-encoded RNA (EBER) transcript.
Results:
8.4% of cases were positive for EBV. Most cases EBV positive were more than 60 years old; male, antrum/pylorus had more frequent localizations. Most cases had an intestinal type and tubular patter and a tendency to better prognostic in comparison EBV negative cases.
Conclusion:
EBV positive GC is an entity with a prevalence of 8.4% in Peru with distinctive clinical and morphological characteristics.
Related Concept Videos
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Mechanisms of Retrovirus-induced Cancers

