Intense sport practices and cardiac biomarkers.
C Le Goff1, J Farré Segura1, P Dufour1
1Department of Clinical Chemistry, University Hospital of Liege, Belgium.
Clinical Biochemistry
|February 26, 2020
Summary
Intense exercise, like running, can elevate cardiac biomarkers. Cardiac fibrosis biomarkers appear most sensitive to the biological effects of strenuous physical activity, offering insights into cardiac adaptation and risk.
Area of Science:
- Cardiology
- Exercise Physiology
- Biomarker Research
Background:
- Cardiac biomarkers are established for diagnosing heart conditions like myocardial infarction and heart failure.
- Exercise typically causes mild to moderate elevations in cardiac biomarkers, but mechanisms remain unclear.
- Potential for increased cardiac risk in undertrained athletes and long-term effects of intensive exercise on heart health are areas of concern.
Purpose of the Study:
- To review existing research on the impact of intense exercise, particularly running, on cardiac biomarkers.
- To elucidate the mechanisms behind exercise-induced cardiac biomarker elevations.
- To identify which cardiac biomarkers are most informative regarding the biological impact of intense physical activity.
Main Methods:
- Literature review summarizing studies on intense exercise and cardiac biomarkers.
- Analysis of cardiac biomarker responses, including troponins and natriuretic peptides.
- Focus on cardiac fibrosis biomarkers and their correlation with exercise intensity.
Main Results:
- Intense exercise, especially running, leads to elevations in various cardiac biomarkers.
- Cardiac fibrosis biomarkers demonstrated significant informativeness regarding the biological impact of intense physical activity.
- The precise mechanisms driving these biomarker changes require further elucidation.
Conclusions:
- Cardiac fibrosis biomarkers are key indicators of the biological impact of intense exercise.
- Understanding these biomarkers can help assess cardiac adaptation and potential risks associated with strenuous physical activity.
- Further research is needed to fully understand the long-term cardiac implications of regular intensive exercise.
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