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Updated: Dec 27, 2025
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A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
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Decreasing Central Line-Associated Bloodstream Infections Acquired in the Home Setting Among Pediatric Oncology
Diane Altounji1, Rachel McClanahan2, Roxanne O'Brien2
1Children's Hospital Los Angeles, Los Angeles, CA, USA.
Summary
Caregiver education for central venous catheters (CVCs) was enhanced with new materials and reinforcement sessions. This initiative aimed to reduce home-acquired central line-associated bloodstream infections (CLABSI) in pediatric cancer patients.
Area of Science:
- Pediatric Oncology
- Infection Control
- Nursing Education
Background:
- Children undergoing cancer treatment often require central venous catheters (CVCs), increasing their risk of central line-associated bloodstream infections (CLABSI).
- Caregivers are responsible for CVC maintenance at home after initial in-hospital education, posing a challenge for infection prevention.
Purpose of the Study:
- To improve the quality of caregiver education for CVC maintenance.
- To reduce the incidence of home-acquired CLABSI in pediatric cancer patients.
Main Methods:
- Literature review informed modifications to the existing caregiver education process.
- Enhanced educational materials included a skills checklist, hygiene handout, and nurse guide.
- Caregivers received two additional CVC care reinforcement sessions with skill redemonstrations.
Main Results:
- While not statistically significant, the preintervention group showed higher odds of mucosal-barrier injury and laboratory-confirmed bloodstream infections.
- Compliance with reinforcement education was measured.
Conclusions:
- Enhanced caregiver education and reinforcement may help reduce home-acquired CLABSI.
- Reducing CLABSI in pediatric cancer patients improves outcomes, decreases hospital stays, and lowers healthcare costs.
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