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Preoperative Cardiac Risk Assessment
David Raslau1, Dennis M Bierle1, Christopher R Stephenson1
1Mayo Clinic Rochester, Division of General Internal Medicine, Rochester, MN.
Insights
Preventing major adverse cardiac events involves preoperative risk assessment and postoperative monitoring. Guidelines vary, with some using functional capacity and others using biomarkers like N-terminal prohormone of brain natriuretic peptide for risk stratification.
Area of Science:
- Cardiology
- Anesthesiology
- Perioperative Medicine
Background:
- Major adverse cardiac events are significant causes of perioperative mortality and morbidity.
- Thorough preoperative risk assessment and postoperative monitoring are crucial for preventing cardiac complications.
Purpose of the Study:
- To review current guidelines and strategies for assessing and managing perioperative cardiac risk.
- To highlight differences in risk assessment approaches between major international guidelines.
Main Methods:
- Review of major American, European, and Canadian guidelines for perioperative cardiac risk assessment.
- Discussion of risk calculators, functional capacity assessment, and biomarker-based strategies.
Main Results:
- Guidelines differ on using functional capacity versus biomarkers (e.g., B-type natriuretic peptide) for guiding postoperative myocardial injury screening.
- Identification of specific conditions (e.g., acute coronary syndrome) that warrant postponing nonemergent surgery.
Conclusions:
- Current guidelines offer varied approaches to perioperative cardiac risk stratification and management.
- The role of biomarkers in guiding interventions for myocardial injury after noncardiac surgery requires further research.
Abstract:
Major adverse cardiac events are common causes of perioperative mortality and major morbidity. Preventing these complications requires thorough preoperative risk assessment and postoperative monitoring of at-risk patients. Major guidelines recommend assessment based on a validated risk calculator that incorporates patient- and procedure-specific factors. American and European guidelines define when stress testing is needed on the basis of functional capacity assessment. Favoring cost-effectiveness, Canadian guidelines instead recommend obtaining brain natriuretic peptide or N-terminal prohormone of brain natriuretic peptide levels to guide postoperative screening for myocardial injury or infarction. When conditions such as acute coronary syndrome, severe pulmonary hypertension, and decompensated heart failure are identified, nonemergent surgery should be postponed until the condition is appropriately managed. There is an evolving role of biomarkers and myocardial injury after noncardiac surgery to enhance risk stratification, but the effect of interventions guided by these strategies is unclear.
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