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Related Experiment Video

Updated: Dec 27, 2025

Fabrication and Characterization of a Conformal Skin-like Electronic System for Quantitative, Cutaneous Wound Management
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Mechanically and biologically skin-like elastomers for bio-integrated electronics.

Shuo Chen1, Lijie Sun1, Xiaojun Zhou2

  • 1State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Belt and Road Joint Laboratory of Advanced Fiber and Low-dimension Materials (Donghua University), College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR China.

Nature Communications
|February 29, 2020
PubMed
Summary

Researchers developed new skin-like elastomers (PSeD-U) with enhanced toughness and strength through hybrid crosslinking. These materials show promise for advanced bio-integrated electronics due to their mechanical and biological properties.

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Area of Science:

  • Materials Science
  • Biomedical Engineering
  • Polymer Chemistry

Background:

  • Bio-integrated electronics require materials mimicking biological tissues.
  • Soft tissues like skin need compliant, tough, elastic, and tear-resistant materials.
  • Existing materials often lack the necessary combination of properties for seamless integration.

Purpose of the Study:

  • To create mechanically and biologically skin-like elastomers.
  • To enhance material properties through a hybrid physical and covalent crosslinking strategy.
  • To demonstrate the potential of these elastomers in bio-integrated electronic devices.

Main Methods:

  • Designed a hybrid crosslinking structure combining physical (hydrogen bonds) and covalent bonds.
  • Synthesized PSeD-U elastomers.
  • Characterized mechanical properties (toughness, strength, modulus, nonlinear behavior).
  • Evaluated cytocompatibility and biodegradability.
  • Fabricated piezocapacitive pressure sensors.

Main Results:

  • PSeD-U elastomers exhibited significantly enhanced toughness (11x) and strength (3x) compared to purely covalently crosslinked elastomers.
  • Materials maintained a low modulus and displayed nonlinear mechanical behavior similar to skin.
  • Demonstrated excellent cytocompatibility and biodegradability.
  • Fabricated sensors showed high pressure sensitivity and rapid response.

Conclusions:

  • The developed PSeD-U elastomers possess skin-like mechanical and biological properties.
  • Hybrid crosslinking, particularly with hydrogen bonds, is an effective strategy for enhancing elastomer performance.
  • These elastomers show significant potential for applications in bio-integrated electronics and tissue engineering.