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Related Concept Videos

Colloidal precipitates01:09

Colloidal precipitates

4.6K
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
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Recrystallization: Solid–Solution Equilibria01:10

Recrystallization: Solid–Solution Equilibria

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Recrystallization is a purification technique used to separate impurities from solid compounds. In this technique, no chemical reactions occur. Instead, it exploits physical properties only, specifically, the solubility differences between the desired compound and impurities, either at a single temperature or at different temperatures, and under other selected conditions. The solid-solution equilibrium (solubility equilibrium) of each component in the solution represents a binary phase...
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Intermolecular Forces in Solutions02:28

Intermolecular Forces in Solutions

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The formation of a solution is an example of a spontaneous process, a process that occurs under specified conditions without energy from some external source.
When the strengths of the intermolecular forces of attraction between solute and solvent species in a solution are no different than those present in the separated components, the solution is formed with no accompanying energy change. Such a solution is called an ideal solution. A mixture of ideal gases (or gases such as helium and argon,...
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Crystal Growth: Principles of Crystallization01:25

Crystal Growth: Principles of Crystallization

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Crystallization is a phase transformation process in which crystals are precipitated from a supersaturated solution or formed from other sources. During crystallization, atoms or molecules arrange themselves into a well-defined, rigid crystal lattice to minimize energy.
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4.5K
Chemical and Solubility Equilibria02:21

Chemical and Solubility Equilibria

4.7K
The free energy change associated with dissolving a solute in a liter of solvent is called the free energy of a solution, ΔGsolution. The overall ΔGsolution is expressed as the balance of ΔGinteraction against the always-favorable free-energy of mixing, ΔGmixing. Solution formation is favorable if  ΔGsolution is less than zero, whereas it is unfavorable if ΔGsolution is greater than zero. In short, for a solution to form and complete dissolution to take place,...
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Energetics of Solution Formation02:35

Energetics of Solution Formation

7.3K
The formation of a solution is an example of a spontaneous process, which is a process that occurs under specified conditions without energy from some external source.
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Updated: Dec 27, 2025

Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
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Interfacial Concentration Effect Facilitates Heterogeneous Nucleation from Solution.

David McKechnie1,2, Samira Anker1, Saraf Zahid1

  • 1Department of Chemical and Process Engineering, University of Strathclyde, 75 Montrose Street, Glasgow G1 1XJ, U.K.

The Journal of Physical Chemistry Letters
|February 29, 2020
PubMed
Summary
This summary is machine-generated.

An oil-solution interface significantly speeds up glycine crystal nucleation compared to an air-solution interface. This discovery, driven by dispersion interactions, offers new insights into controlling heterogeneous nucleation processes.

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Area of Science:

  • Physical Chemistry
  • Materials Science
  • Chemical Engineering

Background:

  • Crystal nucleation from solution is crucial in many fields but poorly understood.
  • Heterogeneous nucleation predominantly occurs at interfaces.

Purpose of the Study:

  • To investigate the effect of different interfaces on glycine crystal nucleation.
  • To elucidate the mechanisms behind interface-accelerated nucleation.

Main Methods:

  • Nucleation experiments using glycine aqueous solutions.
  • Molecular dynamics simulations to analyze interfacial concentrations.

Main Results:

  • An oil-solution interface accelerated glycine nucleation more than an air-solution interface.
  • Simulations revealed enhanced glycine concentration at the oil-solution interface due to dispersion interactions.

Conclusions:

  • Dispersion interactions at oil-solution interfaces can significantly enhance heterogeneous nucleation.
  • This mechanism provides a novel approach for controlling crystal nucleation in various systems.