An Unusual Recurrence of Miller Fisher Syndrome: Three Times in Eight Years

Zeynep Özözen Ayas1, Yeşim Güzey Aras1, Belma Doğan Güngen2

  • 1Sakarya University Training and Research Hospital, Department of Neurology, Sakarya, Turkey.

Noro Psikiyatri Arsivi
|February 29, 2020
PubMed

Insights

Miller Fisher Syndrome (MFS) is a rare autoimmune disorder. This case highlights MFS recurrence three times, suggesting plasma exchange as a treatment option when IVIg is ineffective.

Area of Science:

  • Neurology
  • Autoimmune Diseases

Background:

  • Miller Fisher Syndrome (MFS) is an acute autoimmune polyneuropathy.
  • It typically presents with ataxia, ophthalmoplegia, and areflexia, usually with a good prognosis.

Observation:

  • MFS commonly follows a monophasic course, with rare instances of double recurrence.

Findings:

  • This article details an exceptionally rare case of MFS recurring three times over eight years.

Implications:

  • MFS can exhibit a recurring pattern, challenging typical prognoses.
  • Plasma exchange is a crucial therapeutic consideration for MFS cases with clinical deterioration despite intravenous immunoglobulin (IVIg) treatment.

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