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Candida auris: report of an outbreak
Carme Salvador García1, Nuria Tormo Palop1, Juan Vicente Mulet Bayona1
1Servicio de Microbiología, Consorcio Hospital General Universitario de Valencia, Valencia, España.
Summary
Candida auris is a multidrug-resistant yeast causing deadly infections. This review covers its biology, diagnosis, treatment, and control strategies, detailing a significant outbreak experience.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Public Health
Background:
- Candida auris is an emerging multidrug-resistant yeast.
- It causes serious invasive infections and outbreaks with high mortality.
- Controlling C. auris requires collaboration between laboratories, clinicians, and public health agencies.
Purpose of the Study:
- To review the biology, diagnosis, and treatment of Candida auris infections.
- To present recommendations for C. auris control.
- To describe the experience of a C. auris outbreak in Valencia.
Main Methods:
- Literature review of C. auris biology, diagnosis, and treatment.
- Analysis of expert group recommendations.
- Retrospective analysis of a C. auris outbreak (September 2017 - August 2019).
Main Results:
- The review covers general aspects of C. auris.
- The Valencia outbreak involved 203 colonized/infected patients.
- Thirty invasive infections were diagnosed, with C. auris causing 32% of candidemia in 2018; all strains were fluconazole-resistant.
Conclusions:
- Candida auris presents a significant challenge due to its multidrug resistance and high mortality.
- Effective control necessitates integrated strategies involving diagnostics, treatment, and transmission prevention.
- The Valencia outbreak highlights the need for vigilance and robust public health responses to emerging C. auris threats.
