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Related Concept Videos

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Related Experiment Video

Updated: Dec 27, 2025

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection
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Memory complaints and depressive symptoms over time: a construct-level replication analysis.

Jacqueline Mogle1, Nikki L Hill2, Sakshi Bhargava2

  • 1College of Health and Human Development, Pennsylvania State University, 320D Biobehavioral Health Building, University Park, Pennsylvania, PA, 16802, USA. jam935@psu.edu.

BMC Geriatrics
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Summary
This summary is machine-generated.

Older adults reporting memory decline may develop depressive symptoms later. Depressive symptoms also correlate with memory complaints, but do not predict future memory issues.

Keywords:
Cognitive declineDepressive symptomsMemory complaintsOlder adultsReplication analysis

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Area of Science:

  • Gerontology
  • Cognitive Neuroscience
  • Psychiatry

Background:

  • Memory complaints and depressive symptoms are common in older adults.
  • Both symptoms can indicate future cognitive decline.
  • The temporal relationship between these symptoms is not well understood.

Purpose of the Study:

  • To investigate the concurrent and temporal relationships between memory complaints and depressive symptoms in older adults.
  • To examine bidirectional temporal links between memory complaints and depressive symptoms.

Main Methods:

  • Utilized longitudinal data from the National Health and Aging Trends Study (NHATS) and the Health and Retirement Study (HRS).
  • Analyzed data from over 5000 cognitively intact older adults (aged 65+).
  • Employed an integrative analytic framework to assess relationships over 6-9 years.

Main Results:

  • Perceived memory decline predicted future depressive symptoms.
  • Higher depressive symptoms were associated with higher memory complaints concurrently.
  • Depressive symptoms did not predict future memory complaints; memory ratings predicting depressive symptoms varied across datasets.

Conclusions:

  • Cognitively intact older adults reporting memory decline may be at risk for future depressive symptoms.
  • Replication across datasets is crucial for generalizability of findings.
  • Understanding these temporal links is vital for early intervention in older adults.