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Updated: Dec 27, 2025

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
Published on: December 10, 2012
Probability of error for detecting a change in a parameter and Bayesian Fisher information
Abstract:
The van Trees inequality relates the ensemble mean squared error of an estimator to a Bayesian version of the Fisher information. The Ziv-Zakai inequality relates the ensemble mean squared error of an estimator to the minimum probability of error for the task of detecting a change in the parameter. In this work we complete this circle by deriving an inequality that relates this minimum probability of error to the Bayesian version of the Fisher information. We discuss this result for both scalar and vector parameters. In the process we discover that an important intermediary in the calculation is the total variation of the posterior probability distribution function for the parameter given the data. This total variation is of interest in its own right since it may be easier to compute than the other figures of merit discussed here.
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