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Related Concept Videos

Regulation of Hormone Secretion01:19

Regulation of Hormone Secretion

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Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
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Hormonal Regulation of the Menstrual Cycle01:22

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The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
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Hormonal Control of the Ovarian Cycle01:30

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The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
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Hormonal Regulation01:33

Hormonal Regulation

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The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
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Hormonal Regulation01:40

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Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
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Feedback Loops01:01

Feedback Loops

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In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
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Related Experiment Video

Updated: Dec 27, 2025

Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle
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Editorial: Hormone release patterns in mammals.

Alexander S Kauffman1, Hanne M Hoffmann2

  • 1Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Diego, La Jolla, CA, 92093, USA.

Molecular and Cellular Endocrinology
|March 3, 2020
PubMed
Summary
This summary is machine-generated.

This Special Issue explores hormone release patterns, including circadian rhythms and hypothalamic-pituitary axis function. It examines how these patterns change across life stages and in disease states.

Keywords:
Anterior pituitaryHormoneHypothalamusMelatoninNeuroendocrinePinealPulsesReleaseSecretion

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Area of Science:

  • Endocrinology
  • Physiology
  • Neuroscience

Background:

  • Hormones are crucial for physiological communication and timing of cellular functions.
  • Endocrine systems utilize complex regulatory and feedback mechanisms for precise hormone release.
  • Hormone release patterns are vital for optimizing physiological and cellular processes.

Discussion:

  • This Special Issue investigates various hormone release patterns: ultradian, infradian, pulsatile, and circadian.
  • A key focus is the hypothalamic-pituitary axis and melatonin secretion dynamics.
  • The impact of life stages and disease on these secretion patterns is examined.

Key Insights:

  • Understanding hormone release patterns is essential for comprehending endocrine system regulation.
  • Alterations in hormone secretion patterns are linked to aging and various pathologies.
  • Disruptions in ultradian, infradian, pulsatile, and circadian rhythms can signify disease states.

Outlook:

  • Further research into dynamic hormone release patterns can illuminate disease mechanisms.
  • Investigating changes in hormone secretion across the lifespan offers insights into developmental and aging processes.
  • Targeting aberrant hormone release patterns may lead to novel therapeutic strategies.