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Related Concept Videos

X-ray Imaging01:24

X-ray Imaging

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German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
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X-ray Diffraction of Biological Samples01:10

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X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are  scattered by the electron clouds around the sample atoms. The  X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal...
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Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
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X-ray Crystallography02:18

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The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
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Positron Emission Tomography01:29

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
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Related Experiment Video

Updated: Dec 27, 2025

Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography
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Multibeam ptychography with synchrotron hard X-rays.

Makoto Hirose, Takaya Higashino, Nozomu Ishiguro

    Optics Express
    |March 4, 2020
    PubMed
    Summary

    Multibeam ptychography with synchrotron hard X-rays expands imaging field of view. This technique achieves high spatial resolution for materials science and biology applications.

    Area of Science:

    • X-ray imaging
    • Diffraction microscopy
    • Materials science

    Background:

    • Ptychography is a powerful lensless imaging technique.
    • Current methods are limited by field of view.
    • Synchrotron hard X-rays offer high resolution but require efficient beam utilization.

    Purpose of the Study:

    • To demonstrate multibeam ptychography using synchrotron hard X-rays.
    • To enhance the field of view in ptychographic imaging.
    • To achieve high spatial resolution over a larger area.

    Main Methods:

    • Utilized three mutually incoherent coherent beams generated by multiple slits and focusing mirrors.
    • Measured ptychographic diffraction patterns from a Pt test sample and MnO particles.
    • Reconstructed phase maps using computational methods.

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    Synchrotron X-ray Microdiffraction and Fluorescence Imaging of Mineral and Rock Samples
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    Main Results:

    • Successfully reconstructed phase maps with 25 nm spatial resolution.
    • Achieved a field of view approximately twice as wide as single-beam ptychography.
    • Demonstrated the potential for further field-of-view enlargement through computational simulation.

    Conclusions:

    • Multibeam ptychography effectively enlarges the field of view while maintaining high spatial resolution.
    • The technique shows promise for advanced imaging in materials science and biology.
    • Future work includes simulating setups with more beams to further expand imaging capabilities.