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Design and synthesis of potent PAR-1 antagonists based on vorapaxar

Mengna Fan1, Min Han2, Yan Xia2

  • 1Hebei University of Technology, Tianjin 300100, China; Tianjin Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin 300410, China; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tasly Holding Group Co., Ltd., Tianjin 300410, China.

Bioorganic & Medicinal Chemistry Letters
|March 4, 2020
PubMed

Keywords:
AntiplateletPAR-1 antagonistsStructure-activity relationshipsVorapaxar analogues

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