Long range correlations of the ion current in SV channels. Met3PbCl influence study
Janusz Miśkiewicz1,2, Zenon Trela2, Zbigniew Burdach3
1Institute of Theoretical Physics, University of Wrocław, Wrocław, Poland.
Abstract:
The long-range correlations within the current signal time series of the Beta vulgaris vacuolar membrane under the influence of organolead compound (Met3PbCl) are investigated. The current time series is transformed into a dwell time series. Then the rescaled range and detrended fluctuations analyses are used. It is shown that the presence of Met3PbCl in the solution decreases the mean value of the Hurst exponent and therefore influences the long-range correlations in ionic channel current. This observation is statistically significant. An ion channel model is built and the experimental results reconstructed and analysed.
Related Concept Videos
Ion Channels
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
Voltammetry: Factors Affecting Measurements
Common Ion Effect
Valence Bond Theory
Voltage-gated Ion Channels
Generally, all voltage-gated ion channels have a 'voltage-sensing domain' that spans the lipid bilayer. The charged residues in the sensor move in response to the membrane potential changes that open the channel allowing ions movement. There are several...


