Related Experiment Video
Updated: Dec 27, 2025

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Recurrent severe hypophosphatemia following intravenous iron administration
Melissa Stephanie Nataatmadja1,2, Ross Francis2,3
1Renal Services Sunshine Coast University Hospital and Health Service Birtinya Australia.
Abstract:
Hypophosphatemia postintravenous iron is frequent but under-recognized. If prolonged or recurrent, it can cause osteomalacia. The likely mechanisms are direct toxicity to proximal tubular cells causing phosphate wasting, elevated Fibroblast growth factor-23 (FGF-23), and reduced 1,25-dihydroxyvitamin D (1,25(OH)2D). Hypophosphatemia may be severe and persist for months, necessitating phosphate replacement until normalization of serum levels occurs.
More Related Videos
Related Concept Videos
Chronic Kidney Disease II: Clinical Manifestations
Peritoneal Dialysis III: Nursing Management
Hemodialysis II: Procedure and Complications
Chronic Kidney Disease III: Interprofessional Care
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Introduction to Electrolytes
Role of Sodium
One...

