Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Susceptibility, Permittivity and Dielectric Constant01:26

Susceptibility, Permittivity and Dielectric Constant

2.6K
When placed in an external electric field, a dielectric material gets polarized. The charge density in the dielectric material is given by the sum of the bound and free charge densities, while the total charge density can also be written in terms of the total electric field. The bound charge density can be measured in terms of polarization, leading to the relationship between electric displacement and polarization.
2.6K
Induced Electric Dipoles01:28

Induced Electric Dipoles

4.6K
A permanent electric dipole orients itself along an external electric field. This rotation can be quantified by defining the potential energy because the external torque does work in rotating it. Then, the potential energy is minimum at the parallel configuration and maximum at the antiparallel configuration. While the former is a stable equilibrium, the latter is an unstable equilibrium.
Since the absolute value of potential energy holds no physical meaning, its zero value can be chosen as per...
4.6K
Magnetic Susceptibility and Permeability01:31

Magnetic Susceptibility and Permeability

2.1K
In linear magnetic materials, like paramagnets and diamagnets, magnetization is proportional to the magnetic field intensity. The constant of proportionality, a dimensionless number, is called magnetic susceptibility. The value of the susceptibility depends on the type of material.
When diamagnetic materials are placed under an external magnetic field, the moments opposite to the field are induced. Hence, the susceptibility for diamagnets has a minimal negative value of 10-5–10-6. Since...
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Entropy for Prediction of MACEs in Myocarditis: A Cardiac MRI-based Biomarker of Myocardial Tissue Heterogeneity.

Radiology·2026
Same author

Development of an automated, imaging-based preoperative screening model for early identification of malnutrition in an abdominal surgery cohort.

medRxiv : the preprint server for health sciences·2026
Same author

Cannabis use and glutamate across the psychosis spectrum: in vivo evidence from 7T proton magnetic resonance spectroscopy.

Molecular psychiatry·2026
Same author

The Unique Roles of Executive Function in Co-Occurring Psychopathologies in Autism.

Autism research : official journal of the International Society for Autism Research·2026
Same author

An open, fully-processed data resource for studying mood and sleep variability in the developing brain.

Aperture neuro·2026
Same author

The Hidden Architecture of Brain Structural Variability in 22q11.2 Deletion Syndrome: A Multi-site Study.

medRxiv : the preprint server for health sciences·2026
Same journal

Effectiveness of Ferromagnetic Detectors in Identifying Diabetes Management Devices During Pre-MRI Screening.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Association of Baseline Glymphatic-Related MRI Metrics With Neoadjuvant Chemotherapy-Related Cognitive Impairment in Patients With Breast Cancer.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Editorial for "A Quantitative Modification of VI-RADS for Bladder Cancer at the Ureteral Orifice: A Reader Study on MRI With Varying Experience Levels".

Journal of magnetic resonance imaging : JMRI·2026
Same journal

RF Noise Artifacts From a High Frequency Spinal Cord Stimulation System: A Retrospective Imaging Cohort With Illustrative Cases.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Editorial for "Association Between HIV Infection Duration and Left Ventricular Concentric Remodeling and Myocardial Fibrosis: A Cross-Sectional Study Using Cardiac MRI".

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Editorial for "Effect of Visualized Respiratory Training on Patient Cooperation and Image Quality in Gadoxetic Acid Disodium-Enhanced Liver MRI: A Randomized Controlled Trial".

Journal of magnetic resonance imaging : JMRI·2026
See all related articles

Related Experiment Video

Updated: Dec 27, 2025

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example
08:45

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Published on: October 24, 2012

15.1K

Data-Driven Quantitative Susceptibility Mapping Using Loss Adaptive Dipole Inversion (LADI).

Srikant Kamesh Iyer1, Brianna F Moon2, Nicholas Josselyn1

  • 1Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Journal of Magnetic Resonance Imaging : JMRI
|March 5, 2020
PubMed
Summary
This summary is machine-generated.

Loss adaptive dipole inversion (LADI) offers improved quantitative susceptibility mapping (QSM) by preserving image sharpness and reducing artifacts in neuroimaging and cardiac applications. This data-driven method enhances image quality without relying on spatial edge priors.

Keywords:
Quantitative susceptibility mappingcompressed sensingdipole inversioniron

More Related Videos

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

9.6K
Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
10:33

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

Published on: September 4, 2017

16.4K

Related Experiment Videos

Last Updated: Dec 27, 2025

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example
08:45

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Published on: October 24, 2012

15.1K
Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

9.6K
Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
10:33

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

Published on: September 4, 2017

16.4K

Area of Science:

  • Medical Imaging
  • Biophysics
  • Neuroscience

Background:

  • Quantitative susceptibility mapping (QSM) traditionally relies on prior information for reconstruction, which can introduce inconsistencies, degrade image quality, and smooth essential image features.
  • This limitation necessitates the development of QSM methods that are independent of potentially inaccurate spatial priors.

Purpose of the Study:

  • To develop and evaluate a novel, local field data-driven QSM reconstruction technique.
  • The primary goal is to create a QSM method that does not depend on spatial edge prior information, thereby improving accuracy and image quality.

Main Methods:

  • A retrospective study was conducted using data from the 2016 ISMRM QSM Challenge, including datasets from glioblastoma patients, a microbleed patient, and porcine hearts.
  • 3D gradient echo sequences were acquired on 3T and 7T scanners.
  • The developed method, Loss adaptive dipole inversion (LADI), was compared against established techniques like morphology-enabled dipole inversion (MEDI) and fast nonlinear susceptibility inversion (FANSI) using metrics such as RMSE, SSIM, HFEN, and expert image quality grading.

Main Results:

  • LADI demonstrated excellent correlation with COSMOS and no significant bias, indicating high accuracy.
  • In glioblastoma patients, LADI consistently outperformed MEDI and FANSI in terms of image quality (IQ) and image sharpness (IS) grades and ranks.
  • LADI effectively mitigated artifacts, particularly in cardiac QSM, outperforming MEDI and FANSI in reducing dark artifacts near infarcted regions.

Conclusions:

  • Loss adaptive dipole inversion (LADI) is a robust QSM reconstruction method that preserves fine image features and sharpness, making it suitable for neuroimaging applications involving glioblastoma and microbleeds.
  • LADI shows superior performance in artifact reduction, especially in cardiac QSM, compared to existing methods.