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Updated: Dec 27, 2025

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients

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Development and validation of bioanalytical methods to support investigations of AZD9496 in the clinic

Aaron R Ledvina1, Brian Dayton1, Mark Hoffmann1

  • 1Covance Laboratories, Inc., Madison, WI 53704, USA.

Bioanalysis
|March 5, 2020
PubMed

Keywords:
AZD9496LC–MS/MSSERDbioanalysisclinicaldiastereomeroncologyselective estrogen receptor degrader

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