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Updated: Dec 27, 2025

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
Published on: July 26, 2022
Sowmya Ananthan1, Rafael Benoliel2
1Department of Diagnostic Sciences, Center for Temporomandibular Disorders and Orofacial Pain, Rutgers School of Dental Medicine, 110 Bergen Street, Newark, NJ, 07101, USA.
Chronic orofacial pain (COFP) requires a specific definition beyond the general 3-month rule. Current definitions for orofacial pain and headache focus on pain frequency and duration, not just time.
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