[Perioperative treatment of patients with varicose veins using calcium dobesilate]

Altogether 120 patients with medium to serious forms of varicositas were examined perioperatively after having been divided into 3 groups. Groups I and II were administered perioperatively a daily dosage of 1000 mg (2 x 1 capsule) of the preparation Doxium (Ebewe Arzneimittel GmbH, Unterach am Attersee) during 8 weeks - 2 weeks preoperatively and 6 weeks postoperatively. Group III was used for control purposes. The following was valued as parameter of comparison: kind and seriousness of perioperative trouble, alteration of peripheric oedemas, results of plethysmographic examinations as well as light-reflex-rheography examinations and the post-operative healing-process. Groups I and II (medication of Doxium) showed a significant (p less than 0.05) reduction of the peripheric oedemas already in the preoperative state and postoperatively, the patients had less trouble and a quicker healing-process was observed compared with group III.