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Updated: Dec 27, 2025

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Continuous renal replacement therapy in elderly with acute kidney injury
Kristianne Rachel P Medina-Liabres1, Sejoong Kim1
1Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Acute kidney injury is rising in elderly patients. Continuous renal replacement therapy (CRRT) can be effective, and advanced age does not necessarily predict poor outcomes in critically ill elderly individuals.
Area of Science:
- Nephrology
- Geriatric Medicine
- Critical Care Medicine
Background:
- Acute kidney injury (AKI) incidence is increasing in the elderly.
- Continuous renal replacement therapy (CRRT) is underutilized in older adults.
- Family and healthcare team resistance can impede aggressive interventions in geriatric patients.
Purpose of the Study:
- To increase physician awareness of rising AKI in the elderly.
- To highlight the utility of CRRT in managing AKI in older patients.
- To emphasize a patient-centered approach for elderly individuals requiring critical care.
Main Methods:
- Review of current literature on AKI in the elderly.
- Analysis of CRRT application and outcomes in geriatric populations.
- Identification of prognostic predictors in elderly AKI patients.
Main Results:
- Advanced age alone is not consistently associated with poorer outcomes in AKI.
- Prognostic factors for elderly AKI patients have been identified.
- Patient-centered decision-making is crucial for elderly patients with AKI.
Conclusions:
- Physicians should consider CRRT more readily in elderly patients with AKI.
- Age should not be an absolute contraindication for aggressive AKI management.
- Individualized, patient-centered care improves outcomes for elderly patients with AKI.
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Continuous Renal Replacement Therapy
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Acute Kidney Injury I: Introduction
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