An unusual cause of stridor

Alison Garde1, Tom N Hilliard1, Michael Saunders2

  • 1Department of Paediatric Respiratory Medicine, Bristol Royal Hospital for Children, Bristol, UK.

Insights

A 12-month-old infant with stridor was diagnosed with a mediastinal mass compressing the airway. Imaging confirmed extrinsic compression of the carina and main bronchi, necessitating intervention.

Area of Science:

  • Pediatric Pulmonology
  • Thoracic Imaging
  • Pediatric Oncology

Background:

  • Recurrent stridor in infants can indicate serious underlying pathology.
  • Dexamethasone provided transient relief, suggesting an inflammatory or compressive etiology.

Purpose of the Study:

  • To investigate the cause of persistent stridor in a 12-month-old infant.
  • To characterize the mediastinal mass identified through imaging.

Main Methods:

  • Clinical assessment including physical examination and response to corticosteroids.
  • Diagnostic imaging including chest radiography, flexible nasendoscopy, microlaryngoscopy, bronchoscopy, and CT thorax.
  • Laboratory investigations including complete blood count and C-reactive protein.

Main Results:

  • Chest radiograph revealed left lung hyperexpansion and right bronchial narrowing.
  • Bronchoscopy identified external airway compression at the carina.
  • CT thorax demonstrated a 3cmx2.5cmx1.5cm non-enhancing mediastinal mass extrinsic to the airway, compressing the carina and main-stem bronchi.

Conclusions:

  • A mediastinal mass was the cause of the infant's stridor and respiratory distress.
  • Multimodality imaging is crucial for diagnosing extrinsic airway compression in pediatric patients.
  • Prompt diagnosis and characterization of mediastinal masses are essential for appropriate management.

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