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Updated: Dec 27, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Tools and analytic techniques to synthesise community knowledge in CBPR using computer-mediated participatory system
Joshua Hayward1, Saraya Morton1, Michael Johnstone2
11Global Obesity Centre, Institute for Health Transformation, Deakin University, Geelong, 3220 Australia.
This study introduces STICKE, an online platform for participatory systems modeling, enabling community members to visualize complex health challenges. The findings highlight its effectiveness in generating shared insights for local prevention efforts.
Area of Science:
- Community-based participatory research
- Systems thinking and complexity
- Public health and prevention
Background:
- Participatory systems thinking methods enhance engagement with complex issues in community-based research.
- Insights gained from systems thinking activities predict success in community-based prevention initiatives.
- There is a need for methods that extend the benefits of participation into communities.
Purpose of the Study:
- To test the STICKE (System Thinking In Community Knowledge Exchange) online platform for participatory system modeling.
- To evaluate methods for collating and analyzing outputs from computer-mediated system modeling.
- To assess the utility of generated causal diagrams and summary models for community insights.
Main Methods:
- A group of community members participated in an online, computer-mediated system modeling exercise using STICKE.
- Causal diagrams generated by participants were merged and analyzed using network analysis and DEMATEL.
- A summary model was created to communicate collective insights from the participant group.
Main Results:
- Participants successfully used STICKE to create causal diagrams online.
- The DEMATEL method was preferred by participants for synthesizing individual diagrams into a coherent summary.
- The developed protocol for combining and summarizing causal diagrams was perceived as useful by the participants.
Conclusions:
- STICKE is an accessible tool facilitating online causal diagram creation for community members.
- The study provides a protocol for summarizing participatory system modeling outputs, supporting community understanding of complex problems.
- This approach aids in developing locally owned, sustainable, and effective prevention strategies by understanding community perceptions of health challenges.
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