Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Harnessing washing-driven oxidation to engineer Mo<sub>2</sub>CT<sub><i>x</i></sub>/MoO<sub><i>x</i></sub> hybrid interfaces for energy storage.

Nanoscale·2026
Same author

Programmable ion-protein networks from sodium caseinate: a sustainable platform for soft functional materials.

Materials horizons·2026
Same author

Liquid-Processed 2D Aromatic Amorphous Carbon: Defect Engineering and Universal Transport Scaling.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Function from Confinement: Ligand-Coated Nanoparticles as Functional Materials.

ACS nano·2025
Same author

Plasmonic Metal-Phenolic Network Nanoprobes for Multiplex Dual-Mode Immunophenotyping.

Nano letters·2025
Same author

Tunable Plasmonic Circular Dichroism of Hierarchical Chiral Assemblies.

Chemistry of materials : a publication of the American Chemical Society·2025

Related Experiment Video

Updated: Dec 27, 2025

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs
03:33

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs

Published on: November 17, 2023

3.1K

SERS-Based Molecularly Imprinted Plasmonic Sensor for Highly Sensitive PAH Detection.

Alexander Castro-Grijalba1,2, Verónica Montes-García1, María José Cordero-Ferradás1

  • 1Centro Singular de Investigaciones Biomédicas (CINBIO) y Departamento de Quı́mica Fı́sica, Universidade de Vigo, 36310 Vigo, Spain.

ACS Sensors
|March 6, 2020
PubMed
Summary

A new Au@MIP platform combines polymers and gold nanoparticles for sensitive surface-enhanced Raman scattering detection of polycyclic aromatic hydrocarbons (PAHs). This hybrid sensor offers a 100-fold improvement for ultradetection in real-world samples.

Keywords:
SERSenvironmental analysishybrid nanostructuresmolecularly imprinted polymersplasmonic sensorspolycyclic aromatic hydrocarbons

More Related Videos

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

12.5K
Author Spotlight: Revolutionizing Microfluidics Through Microchannel Fabrication on Nanopaper
03:58

Author Spotlight: Revolutionizing Microfluidics Through Microchannel Fabrication on Nanopaper

Published on: October 6, 2023

2.2K

Related Experiment Videos

Last Updated: Dec 27, 2025

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs
03:33

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs

Published on: November 17, 2023

3.1K
Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

12.5K
Author Spotlight: Revolutionizing Microfluidics Through Microchannel Fabrication on Nanopaper
03:58

Author Spotlight: Revolutionizing Microfluidics Through Microchannel Fabrication on Nanopaper

Published on: October 6, 2023

2.2K

Area of Science:

  • Nanotechnology
  • Spectroscopy
  • Materials Science

Background:

  • Polycyclic aromatic hydrocarbons (PAHs) are environmental pollutants requiring sensitive detection methods.
  • Surface-enhanced Raman scattering (SERS) offers high sensitivity but requires effective substrates.
  • Molecularly imprinted polymers (MIPs) provide selective molecular recognition capabilities.

Purpose of the Study:

  • To develop a novel hybrid plasmonic platform (Au@MIP) for enhanced SERS detection of PAHs.
  • To investigate the fabrication and characterization of the Au@MIP platform.
  • To evaluate the sensitivity, selectivity, and applicability of the Au@MIP sensor for PAH detection.

Main Methods:

  • Fabrication of Au@MIP hybrid platform via layer-by-layer deposition of gold nanoparticles (Au NPs) and MIP thin film coating.
  • Tailoring MIP film thickness and homogeneity using parameters like prepolymerization time and spin-coating rate.
  • Utilizing pyrene or fluoranthene as template molecules for MIP fabrication and subsequent SERS analysis.

Main Results:

  • The Au@MIP platform demonstrated ultradetection of template PAHs in the nanomolar (nM) regime.
  • A 100-fold improvement in sensitivity was achieved compared to non-imprinted sensors (Au@NIPs).
  • The selectivity of the Au@MIP sensor was influenced by the choice of template molecule, and its applicability was confirmed in real water samples.

Conclusions:

  • The developed Au@MIP platform is a promising tool for sensitive and selective SERS detection of PAHs.
  • The hybrid approach synergistically combines MIP recognition with Au NP plasmon enhancement.
  • This technology holds potential for environmental monitoring, food safety, and biomedical applications.