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Extracorporeal membrane oxygenation for the support of pediatric patients with acute fulminant myocarditis
Güntülü Şık1, Agageldi Annayev1, Asuman Demirbuğa1
1Departments of Pediatric Intensive Care Unit, Acıbadem Mehmet Ali Aydınlar University, School of Medicine, İstanbul, Turkey.
Insights
Extracorporeal membrane oxygenation (ECMO) effectively supports pediatric patients with acute fulminant myocarditis. This life-saving technology improves survival rates for children with severe myocarditis resistant to medical treatment.
Area of Science:
- Pediatric Cardiology
- Critical Care Medicine
- Cardiovascular Surgery
Background:
- Acute fulminant myocarditis is a severe, rapidly progressive cardiac disease in children.
- Outcomes for children with severe, treatment-resistant acute myocarditis are often poor.
- Extracorporeal membrane oxygenation (ECMO) is a potential life-support intervention.
Purpose of the Study:
- To evaluate the clinical outcomes of pediatric patients with acute fulminant myocarditis treated with ECMO.
- To assess the effectiveness and safety of ECMO in this critical patient population.
- To determine factors influencing survival in pediatric acute fulminant myocarditis.
Main Methods:
- Retrospective chart review of six pediatric patients with acute fulminant myocarditis.
- Analysis of demographic data, clinical presentation, vital signs, and laboratory results.
- Documentation of ECMO duration, intensive care unit stay, and complications.
Main Results:
- The median age of patients was 63 months, with a median ECMO duration of 164 hours.
- Common symptoms included chest pain and fever; severe arrhythmias occurred in two patients.
- A significant survival rate of 83.3% was observed, with patients discharged successfully.
Conclusions:
- ECMO serves as an effective circulatory support for pediatric patients with acute fulminant myocarditis.
- Timely initiation of ECMO can enhance survival rates and lead to better patient outcomes.
- ECMO facilitates myocardial recovery while providing essential hemodynamic support.
Abstract:
Şık G, Annayev A, Demirbuğa A, Deliceo E, Aydın S, Erek E, Demir Hİ, Çıtak A. Extracorporeal membrane oxygenation for the support of pediatric patients with acute fulminant myocarditis. Turk J Pediatr 2019; 61: 867-872. Acute fulminant myocarditis, is a severe, rapidly progressive disease. The clinical outcomes of children with severe acute myocarditis who are resist to medical treatment is not well known. We studied the clinical courses of patients with acute fulminant myocarditis supported by extracorporeal membrane oxygenation (ECMO). We performed a retrospective chart review of six children with acute fulminant myocarditis who were treated with ECMO. Demographic information, clinical and vital signs, as well as laboratory results were investigated. The median age of 63 months (13-140 months), the mean ECMO duration was 164 hours (79-402 hours), and median intensive care unit stay was 24 days. The most common symptoms were chest pain (66%) and fever (66%). Severe arrhythmia were seen in two patients. One patient received extracorporeal cardiopulmonary resuscitation. In two patients, right femoral arteries and right femoral veins were used, in others, right common carotid artery and right internal jugular veins were used. Five patients (83.3 %) survived to discharge. ECMO can be used effectively in pediatric patients with acute fulminant myocarditis to support the circulation while awaiting myocardial recovery. Timely use of ECMO can improve the survival rate and may be associated with better outcomes.
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