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TREM2: Modulator of Lipid Metabolism in Microglia

Eyiyemisi C Damisah1, Anupama Rai2, Jaime Grutzendler3

  • 1Department of Neurology, Yale School of Medicine, New Haven, CT, USA; Department of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.

Neuron
|March 6, 2020
PubMed

Keywords:
ApoETrem2cholesterol transportdemyelinationlipidomicsmicroglianeurodegeneration

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Antiepileptic drugs, such as levetiracetam (Keppra) and brivaracetam (Briviact), have emerged as crucial tools in managing epilepsy. These medications exert their therapeutic effects by targeting the synaptic vesicle protein SV2A, a transmembrane glycoprotein primarily found in the brain.
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