Percutaneous coronary intervention in aorto-ostial coronary chronic total occlusion: outcomes and technical

Soledad Ojeda1, Aurora Luque1, Manuel Pan1

  • 1Departamento de Cardiología, Hospital Reina Sofía, Universidad de Córdoba, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain.

Insights

Percutaneous coronary intervention (PCI) for aorto-ostial chronic total coronary occlusion (CTO) is challenging. Successful PCI is achievable with experienced operators, particularly when interventional collaterals enable a retrograde approach.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Vascular Medicine

Background:

  • Aorto-ostial chronic total coronary occlusion (CTO) presents unique challenges for percutaneous coronary intervention (PCI).
  • Optimizing PCI strategies for this specific lesion subset is crucial for improving patient outcomes.

Purpose of the Study:

  • To analyze the technical aspects and outcomes of PCI in patients with aorto-ostial CTO.
  • To identify factors influencing procedural success and complications in this challenging group.

Main Methods:

  • A multicenter registry included 103 patients undergoing aorto-ostial CTO PCI between February 2013 and December 2018.
  • Technical and procedural success rates, crossing techniques, and complications were analyzed.

Main Results:

  • Technical and procedural success rates were 76.7% and 75.7%, respectively.
  • The retrograde approach was the most successful crossing technique (62.0%), particularly with interventional collaterals.
  • Absence of interventional collaterals was the only independent predictor of technical failure (OR, 12.38).
  • Complications included coronary perforation (3.9%) and stroke (1.9%).
  • At a median follow-up of 31 months, cardiovascular death occurred in 2.9% and repeat revascularization in 12.6%.

Conclusions:

  • Aorto-ostial CTOs are a difficult subset for PCI, but acceptable success rates and favorable outcomes are achievable.
  • Experienced operators and the utilization of the retrograde approach, facilitated by interventional collaterals, are key to successful PCI in this population.
Abstract

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
152
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
186
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
186
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
268