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Skull Abnormalities in Cadavers in the Gross Anatomy Lab
Jessica De Rose1, Brian Laing1, Maha Ahmad2
1University of Detroit Mercy School of Dentistry, USA.
Biomed Research International
|March 10, 2020
Summary
Abnormal skull bone growth, potentially hypertosis frontalis interna (HFI), was observed in 29% of cadavers. This study suggests HFI may be a significant factor in these skull abnormalities, with higher prevalence than previously reported.
Area of Science:
- Anatomy
- Pathology
- Osteology
Background:
- The skull protects the brain, and its living bone tissue undergoes constant remodeling.
- Abnormal bone growth patterns in skulls can arise from various intrinsic and extrinsic factors.
- This study investigated potential causes of skull abnormalities observed in cadaver dissections.
Purpose of the Study:
- To investigate the causes of abnormal bone growth patterns observed in human cadaver skulls.
- To identify potential links between skull abnormalities and conditions like hypertosis frontalis interna (HFI) and Paget's disease.
Main Methods:
- Examined 65 formalin-embalmed cadaver heads from Detroit Mercy School of Dentistry (2016-2019).
- Recorded age, sex, and medical history of specimens.
- Evaluated skulls for signs of bone disease, including hypertosis frontalis interna (HFI) and Paget's disease.
Main Results:
- 19 specimens (29%) exhibited irregular thickening of the frontal bone's internal surface, resembling HFI or Paget's disease.
- Females (63%) were more affected than males (36%) among those with abnormalities.
- Five specimens (26%) had pre-existing neurological disorders (Alzheimer's, dementia, Parkinson's).
Conclusions:
- Hypertosis frontalis interna (HFI) is a potential contributor to observed skull abnormalities.
- The study found a higher prevalence of skull abnormalities than previously reported.
- Further research involving biopsy and radiological examination is recommended to confirm causes like HFI, Paget's disease, or hormonal imbalances.
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