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Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
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Bio-Inductive Materials in Direct and Indirect Pulp Capping-A Review Article
Marta Kunert1, Monika Lukomska-Szymanska1
1Department of General Dentistry, Medical University of Lodz, 251 Pomorska St., 92-213 Lodz, Poland.
Materials (Basel, Switzerland)
|March 12, 2020
Summary
Mineral trioxide aggregate (MTA) remains the most validated material for pulp capping. While Biodentine shows promise, further long-term studies are needed, and evidence for TheraCal LC and ACTIVA BioACTIVE in vital pulp therapy is insufficient.
Area of Science:
- Dentistry
- Biomaterials Science
Background:
- Pulp capping aims to preserve pulp vitality using bioactive materials.
- Various calcium-silicate cements, light-cured materials, and glass-ionomers are used.
Purpose of the Study:
- To analyze and compare bio-inductive materials for direct and indirect pulp capping.
- To evaluate the properties and clinical performance of selected materials.
Main Methods:
- Review and correlation of in vitro and in vivo data.
- Comparison of four calcium-silicate cements (MTA, Biodentine), a light-cured material (TheraCal LC), and a glass-ionomer (ACTIVA BioACTIVE).
Main Results:
- Mineral trioxide aggregate (MTA) is the most validated material for pulp capping.
- Biodentine offers easier handling and predictable outcomes but requires more long-term clinical data.
- Insufficient evidence supports TheraCal LC or ACTIVA BioACTIVE for vital pulp therapy.
Conclusions:
- MTA is currently the gold standard for pulp capping procedures.
- Biodentine shows potential but needs further long-term clinical validation.
- TheraCal LC and ACTIVA BioACTIVE lack sufficient evidence for vital pulp therapy applications.

