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Updated: Dec 26, 2025

Simple Continuous Glucose Monitoring in Freely Moving Mice
Published on: February 24, 2023
Monitoring free flap venous congestion using continuous tissue glucose monitoring: A case report
Kazufumi Tachi1, Shuichi Nakatsukasa1, Yui Nakayama1
1Plastic and Reconstructive Surgery, Asahi General Hospital, I-1326, Asahi-Shi, Chiba-Ken 289-2511, Japan.
Abstract:
Blood glucose levels (BGLs) are a good indicator of postoperative venous congestion caused by a thrombus at the anastomotic site of a free flap. Tissue glucose levels (TGLs) are believed to be superior to BGLs for two reasons: TGLs are thought to represent a tissue's congestive status more directly than BGLs and are able to be measured by a continuous tissue glucose monitoring device (CTGMD), whereas BGLs must be measured manually by sampling the flap, hindering the patient's sleep and increasing the nurse's workload. A case is described in which a postoperative thrombus developed in a free flap vein three times. TGL in the flap was monitored by a CTGMD (Free Style Libre®, Abbott, U.S.A.), and BGL was monitored in parallel by conventional sampling of the flap. When venous congestion developed at the anastomotic site, TGLs decreased faster than BGLs; after the congestion was ameliorated by exsanguination, BGLs increased faster than TGLs, indicating that TGLs are a better indicator of venous thrombosis at the anastomotic site than BGLs.
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