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Updated: Dec 26, 2025

Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay
Published on: September 7, 2018
[Studying the possibility of using immuno-enzy test system for evaluating anti-pertussis immunity.]
O Y Sosnina1, A M Nikolaeva1, T V Vyaznikova2
1Submittal of Federal State Unitary Enterprise "Scientific and Production Association for Immunological Preparations "Microgen" of the Ministry of Health of the Russian Federation, 614089, Perm, Russia.
Abstract:
A research objective - to study the possibility of using the ELISA Anti-K enzyme immunoassay system to evaluate anti-pertussis immunity. А comparative assessment of the content of co-crank antibodies in the blood serum of adults, pregnant women and children 6 years old in the agglutination test, in the test system "Anti-K ELISA" and test systems of foreign production was carried out. The "Anti-K" IFA test system makes it possible to detect the level of specific antibodies to both the whole cell and cell-free pertussis component of the vaccine at any stage of the vaccination cycle. This diagnostic test can be used to determine the tactics of immunization, and to assess population immunity.

