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Published on: July 29, 2019
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Laser Therapy Induces Increased Viability and Proliferation in Isolated Fibroblast Cells.
Nihal Kara1, Hilal Selamet2, Yasin Atakan Benkli3
1Department of Pedodontics, Faculty of Dentistry, Ordu University, Ordu, Turkey.
Wounds : a Compendium of Clinical Research and Practice
|March 13, 2020
Summary
Laser therapy (LT) enhances fibroblast cell proliferation, crucial for wound healing in dental applications. Optimal results were seen with specific power outputs and application frequencies, suggesting LT
Area of Science:
- Biomedical Engineering
- Cell Biology
- Dental Science
Background:
- Laser therapy (LT) is utilized in dental treatments to stimulate biological processes.
- Its potential to enhance wound healing is a key area of interest.
Purpose of the Study:
- To investigate the in vitro effects of LT on fibroblast cell proliferation.
- To determine if LT can promote wound healing.
Main Methods:
- Fibroblast cell cultures were irradiated with an Nd:YAG laser at varying power outputs (0.5W-3W) and application frequencies (1-3 times).
- Cell proliferation was assessed using the MTT assay 24 hours post-irradiation.
Main Results:
- Fibroblast proliferation increased with LT, particularly at 1W and 2W power outputs.
- Two to three applications of LT resulted in greater proliferation compared to a single application.
- The highest proliferation was observed at 1W with two applications.
Conclusions:
- LT effectively increases fibroblast cell proliferation in a dose-dependent manner (power and frequency).
- These findings support the use of LT for improving wound healing in oral surgery and periodontal treatments.
