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Prostate biopsy techniques and pre-biopsy prophylactic measures: variation in current practice patterns in the
Sofie C M Tops1, Evert L Koldewijn2, Diederik M Somford3
1Department of Medical Microbiology, Radboud Center Infectious Diseases, Radboudumc, huispost 777, Geert Grooteplein Zuid 10, 6525, GA, Nijmegen, the Netherlands. sofie.tops@radboudumc.nl.
BMC Urology
|March 14, 2020
Summary
Dutch urologists show varied practices in prostate biopsy (PB) techniques and antibiotic prophylaxis. Increasing antibiotic resistance is a growing concern, highlighting the need for standardized, evidence-based recommendations for prophylaxis.
Area of Science:
- Urology
- Infectious Diseases
- Public Health
Background:
- Evolving prostate biopsy (PB) procedures and techniques necessitate updated clinical practices.
- Increasing antibiotic resistance impacts the efficacy of pre-biopsy prophylactic regimens.
- Variability in hospital practices may arise due to differing responses to antibiotic resistance.
Purpose of the Study:
- To determine current prostate biopsy (PB) practices in the Netherlands.
- To assess variability in PB techniques and antimicrobial prophylaxis across Dutch hospitals.
- To understand Dutch urologists' perceptions of fluoroquinolone resistance and biopsy-related infections.
Main Methods:
- An online questionnaire was distributed to 420 members of the Dutch Association of Urology.
- Data collected included PB techniques, periprocedural antimicrobial prophylaxis, and urologists' perceptions.
- Descriptive statistical analysis was performed on 161 responses from 65 hospitals.
Main Results:
- Transrectal ultrasound-guided prostate biopsy (TRUSPB) is used in 98.5% of hospitals; other image-guided techniques are also employed.
- Significant variation exists in prophylactic regimens, with ciprofloxacin being most common (84.4%).
- 25.2% of urologists face current ciprofloxacin resistance issues, with 73.6% anticipating future problems.
Conclusions:
- Wide variation in prostate biopsy (PB) practice patterns and antimicrobial prophylaxis exists among Dutch urologists.
- TRUSPB remains dominant, but image-guided techniques are gaining traction.
- Lack of standardized, evidence-based recommendations for prophylaxis is evident, especially considering rising antibiotic resistance.
