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Factors Determining Diabetic Remission after Sleeve Gastrectomy: A Prospective Study
Rohit Jindal1, Mayank Gupta1, Ashish Ahuja1
1Department of General Surgery, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Summary
Laparoscopic sleeve gastrectomy (LSG) effectively treats type 2 diabetes mellitus (T2DM) and obesity, achieving significant weight loss and diabetes remission in most patients. Early intervention in younger, less severe cases yields better outcomes.
Area of Science:
- Bariatric Surgery
- Metabolic Surgery
- Endocrinology
Background:
- Rising global obesity and type 2 diabetes mellitus (T2DM) rates drive bariatric surgery demand.
- Laparoscopic sleeve gastrectomy (LSG) shows promise for weight loss and glycemic control.
Purpose of the Study:
- Evaluate LSG outcomes for T2DM remission.
- Identify predictors of diabetes remission post-LSG.
Main Methods:
- Prospective study of 104 obese T2DM patients undergoing LSG.
- Assessed weight loss, BMI, and glycemic control over 6 months.
- Statistical analysis using Student's t-test and Chi-square tests.
Main Results:
- LSG achieved significant excess weight loss (EWL) of 60.75%.
- 78.9% of patients achieved diabetes remission with improved glycemic markers.
- Younger, heavier patients with shorter disease duration and milder severity showed better remission rates.
Conclusions:
- LSG is a successful treatment for T2DM in obese patients.
- Optimal candidates are younger, obese individuals with mild, short-duration T2DM.
- LSG should be considered earlier in treatment, not as a last resort.
