Related Experiment Video
Updated: Dec 26, 2025

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Influence of overweight and obesity on acute appendicitis in children. A cohort study
C Delgado-Miguel1, A J Muñoz-Serrano1, S Barrena Delfa1
1Pediatric Surgery Department. Hospital Universitario La Paz. Madrid (Spain).
Insights
Overweight and obese children with appendicitis face increased risks of surgical wound infections and dehiscence. This study highlights the importance of considering body mass index (BMI) in pediatric appendicitis outcomes.
Area of Science:
- Pediatric Surgery
- Obesity Research
- Clinical Outcomes
Background:
- Postsurgical complications in acute appendicitis are linked to overweight and obesity in adults.
- Limited research exists on these effects in pediatric populations.
- Investigating BMI's impact on pediatric appendicitis is crucial.
Purpose of the Study:
- To analyze the influence of overweight and obesity on the postoperative course of acute appendicitis in children.
- To compare complication rates between normal weight and overweight/obese pediatric patients.
Main Methods:
- A prospective cohort study included 403 pediatric patients undergoing appendicitis surgery.
- Patients were categorized into overweight-obese and normal weight cohorts based on BMI.
- Outcomes assessed included operating time, hospital stay, and early postoperative complications.
Main Results:
- Overweight-obese children experienced longer operating times compared to normal weight children.
- The overweight-obese group had significantly higher rates of surgical wound infection and wound dehiscence.
- No significant differences were found in intra-abdominal abscess rates or hospital stay.
Conclusions:
- Overweight and obese children with appendicitis exhibit a greater risk of developing surgical wound infections and dehiscence.
- These findings underscore the need for tailored perioperative management in pediatric appendicitis patients with higher BMI.
Introduction:
Overweight and obesity are risk factors for the development of postsurgical complications in acute appendicitis in adults. However, there are few studies that evaluate their effects in pediatric patients. We aim to analyze their influence on the postoperative course of acute appendicitis in children.
Material And Methods:
A prospective cohort study was performed in patients undergoing surgery for acute appendicitis in 2017-2018, divided into two cohorts according to BMI adjusted to sex and age, following the WHO criteria: exposed cohort (overweight-obese) and non-exposed cohort (normal weight). Clinical follow-up was performed during hospital admission and one month after surgery. Demographic variables, operating time, average hospital stay, and early postoperative complications (wound infection, wound dehiscence, and intra-abdominal abscess) were assessed.
Results:
A total of 403 patients were included (exposed cohort n=97 and non-exposed cohort n=306), with no differences in sex or age. A longer operating time was observed in the exposed cohort (57.6 ± 22.5 vs. 44.6 ± 18.2 min, p<0.001), with no differences found according to the surgical approach (open surgery or laparoscopic surgery) used. This group also had a higher surgical wound infection rate as compared to the non-exposed cohort (10.3% vs. 4.2%; RR: 1.90; CI: 95% [1.15-3.14], p<0.001), as well as a higher surgical wound dehiscence rate (7.2% vs. 2.3%; RR: 2.16; CI: 95% [1.24-3.76], p<0.001). No differences in the development of intra-abdominal abscesses or in hospital stay were observed.
Conclusions:
Obese and overweight children with appendicitis have a higher risk of developing postoperative complications such as wound infection and dehiscence than normal weight patients.
More Related Videos
Related Concept Videos
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Obesity
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Drug Dosing: Obese Patients
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

