Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Waves01:23

Brain Waves

3.6K
Brain waves are electrical signals generated by the neurons in the brain, which are regularly monitored to measure mental activities. Brain waves and their frequency ranges can be measured using an electroencephalogram or EEG. There are four main types of brain waves, each with distinct characteristics:
3.6K
Action Potential01:14

Action Potential

10.4K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
10.4K
Neuronal Communication01:28

Neuronal Communication

2.8K
Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
2.8K
The Role of Ion Channels in Neuronal Computation01:19

The Role of Ion Channels in Neuronal Computation

3.5K
A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
3.5K
Propagation of Action Potentials01:23

Propagation of Action Potentials

8.5K
The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
8.5K
Neurons: The Axon01:21

Neurons: The Axon

6.6K
Axons are long, cytoplasmic processes of nerve cells capable of propagating electrical impulses known as action potentials. The cytoplasm or axoplasm of an axon contains neurofibrils, neurotubules, small vesicles, lysosomes, mitochondria, and various enzymes, all encased within the axolemma, the plasma membrane of the axon.
The axon attaches to the cell body at a cone-shaped elevation called the axon hillock. The initial part of the axon, closest to the hillock, is known as the initial segment....
6.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An ECG biomarker for sudden cardiac death discovered with deep learning.

Nature·2026
Same author

Prenatal and postnatal household air pollution and longitudinal growth trajectories: results from long-term follow up of the GRAPHS cohort.

Environment international·2026
Same author

Nerve growth factor receptor p75NTR interacts with Toll-like receptor 4 and the alarmins high mobility group box 1 and nucleophosmin: a novel inflammatory mechanism in psoriasis.

The British journal of dermatology·2026
Same author

Genetic Markers of Tumor Multiplicity in Non-melanoma Skin Cancer: Associations of 19 SNPs in an Italian Cohort.

Dermatology and therapy·2026
Same author

Isoscapes as a Regional-Scale Tool for Tracing Groundwater Uranium Cycling in the Northern Plains, United States.

Environmental science & technology·2025
Same author

Physical Exercise or Cognitive Behavioral Therapy for Takotsubo Cardiomyopathy: A Randomized Controlled Trial.

Circulation. Heart failure·2025

Related Experiment Video

Updated: Dec 26, 2025

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

5.6K

Brain-wave equation incorporating axodendritic connectivity.

James Ross1, Michelle Margetts1, Ingo Bojak2

  • 1Centre for Mathematical Medicine and Biology, School of Mathematical Sciences, University of Nottingham, Nottingham NG7 2RD, United Kingdom.

Physical Review. E
|March 15, 2020
PubMed
Summary

We developed a new neural field model incorporating dendritic structure to simulate brain waves. This model reveals how passive dendritic properties influence the speed and shape of traveling cortical waves.

More Related Videos

Analyzing Neural Activity and Connectivity Using Intracranial EEG Data with SPM Software
06:50

Analyzing Neural Activity and Connectivity Using Intracranial EEG Data with SPM Software

Published on: October 30, 2018

9.8K
Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

6.0K

Related Experiment Videos

Last Updated: Dec 26, 2025

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

5.6K
Analyzing Neural Activity and Connectivity Using Intracranial EEG Data with SPM Software
06:50

Analyzing Neural Activity and Connectivity Using Intracranial EEG Data with SPM Software

Published on: October 30, 2018

9.8K
Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

6.0K

Area of Science:

  • Computational Neuroscience
  • Mathematical Biology
  • Neurophysics

Background:

  • Neural field models are crucial for understanding large-scale brain activity.
  • Dendritic structure and axodendritic connectivity play significant roles in neural signal processing.
  • Efficient simulation methods are needed to study complex neural dynamics.

Purpose of the Study:

  • To introduce an integral model of a two-dimensional neural field with a third dimension for dendritic space.
  • To develop an equivalent brain-wave partial differential equation for efficient numerical simulation.
  • To investigate the impact of passive dendritic properties on traveling cortical waves.

Main Methods:

  • Developed an integral neural field model incorporating dendritic tree spatial dimension.
  • Incorporated realistic patterns of axodendritic connectivity.
  • Derived an equivalent brain-wave partial differential equation for computational analysis.

Main Results:

  • Successfully constructed a partial differential equation enabling efficient model simulation.
  • Demonstrated the influence of dendritic structure on wave propagation.
  • Highlighted how passive dendritic properties affect the speed and shape of traveling cortical waves.

Conclusions:

  • The integral neural field model with dendritic space provides a powerful tool for studying neural dynamics.
  • Passive dendritic properties significantly modulate the characteristics of large-scale cortical waves.
  • The derived partial differential equation facilitates efficient simulation and analysis of neural wave phenomena.