Ringing bells: Morganella morganii fights for recognition
1College of Medicine, Jouf University, PO Box: 2014, Sakaka, Al Jouf, Saudi Arabia.
Public Health
|March 15, 2020
Summary
Morganella morganii infections are increasing globally, showing concerning resistance patterns. This opportunistic pathogen poses a significant threat, potentially becoming the next superbug due to evolving virulence and resistance.
Area of Science:
- Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Background:
- Opportunistic microbial infections are rising globally.
- Morganella morganii (M. morganii) is an increasingly reported opportunistic pathogen.
- Understanding its spectrum of diseases, pathogenicity, and resistance is crucial.
Purpose of the Study:
- To review the diversified disease spectrum of M. morganii.
- To analyze the pathogenicity and resistance patterns of M. morganii.
- To assess the clinical significance and public health implications of M. morganii infections.
Main Methods:
- A comprehensive literature review was conducted.
- Articles were sourced from PubMed and Google Scholar.
- Search terms included 'M. morganii', 'prevalence', 'virulence factors', 'infections', 'resistance pattern', and 'genomics'.
Main Results:
- M. morganii is a significant clinical pathogen with increasing occurrence and resistance rates.
- Gene and plasmid transfer contribute to the evolution of virulence in M. morganii and other pathogens.
- Its broad host range suggests potential for novel infections.
Conclusions:
- M. morganii opportunism is globally increasing, with accumulating multidrug resistance genes.
- This leads to higher morbidity and mortality, complicating treatment.
- M. morganii must be recognized as a clinically significant pathogen for patient care and infection control.
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