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In Vivo Models for Pathotyping and Vaccine Efficacy for Swine Influenza
Kelly M Lager1, Amy L Vincent2
1Virus and Prion Research Unit, US Department of Agriculture, Agricultural Research Service, National Animal Disease Center, Ames, IA, USA. kelly.lager@usda.gov.
Methods in Molecular Biology (Clifton, N.J.)
|March 15, 2020
Abstract:
Swine influenza is a disease of the respiratory tract caused by influenza A virus (IAV). Experimental inoculation of pigs involves either aerosolization of virus and inhalation or the direct introduction of virus into the upper or lower respiratory tract. This chapter covers methods for experimental IAV infection of pigs and collection of specific samples to study the pathogenesis of swine influenza and vaccine efficacy.
