Ligneous gingivitis secondary to plasminogen deficiency: a multidisciplinary diagnostic challenge

Area of Science:

• Genetics
• Oral Medicine
• Pathology

Background:

• Plasminogen deficiency is a rare genetic disorder characterized by fibrin deposition in mucosal tissues.
• Clinical manifestations typically involve the eyes, with oral lesions affecting the gingiva.

Observation:

• A young male patient presented with ligneous gingivitis as the sole clinical sign.
• The patient had no other apparent clinical lesions associated with plasminogen deficiency.

Findings:

• Ligneous gingivitis can occur in the absence of other typical clinical manifestations of plasminogen deficiency.
• This isolated presentation poses diagnostic challenges for dental professionals.

Implications:

• Increased awareness among dentists and specialists is crucial for timely diagnosis of plasminogen deficiency.
• Early diagnosis can prevent potential complications and guide appropriate management strategies.