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The role of Caesarean section in childhood asthma
A Q Al Yassen1, J N Al-Asadi2, S K Khalaf3
1FRACGP College of Medicine, Basrah University, Iraq
Insights
Children born via Caesarean section face a significantly higher risk of developing childhood asthma. This study confirms a strong association between C-section delivery and increased asthma incidence in children.
Area of Science:
- Pediatrics
- Epidemiology
- Public Health
Background:
- Previous research suggests a link between Caesarean section (C-section) delivery and increased asthma risk in children.
- Understanding this association is crucial for public health initiatives and clinical practice.
Purpose of the Study:
- To investigate the association between Caesarean section delivery and the risk of childhood asthma.
- To identify risk factors contributing to asthma development in children.
Main Methods:
- A case-control study was conducted in Basrah, Iraq, involving 952 children aged 3-12 years.
- Asthmatic cases (n=407) and age-matched non-asthmatic controls (n=545) were enrolled.
- Binary logistic regression analysis was employed to assess the relationship between birth method and asthma.
Main Results:
- Delivery via Caesarean section was identified as an independent significant risk factor for childhood asthma (Odds Ratio=3.37).
- Other significant predictors of asthma included bottle feeding (OR=27.29) and low birth weight (OR=16.7).
- Approximately 29.7% of the study participants were delivered via Caesarean section.
Conclusions:
- Caesarean section delivery is significantly associated with an elevated risk of childhood asthma.
- The findings underscore the importance of considering delivery mode in asthma risk assessment.
- Further research may explore underlying mechanisms linking C-section to asthma development.
Objective:
As indicated by previous studies, children born via Caesarean section may have an increased risk of developing asthma compared with those born via vaginal delivery. The aim of this study is to assess the association between a Caesarean section and the risk of childhood asthma. Methods: This was a case-control study carried out in Basrah, Iraq including 952 children aged 3-12 years. Four hundred and seven asthmatic cases and a control group of 545 age-matched non-asthmatic children were enrolled. Binary logistic regression was used to assess the relationship between asthma and birth via Caesarean section.
Results:
The mean age of the children was 6.7±2.5 years. Two-hundred eighty-three children (29.7%) were delivered via Caesarean section. The binary logistic regression analysis showed that delivery via Caesarean section was found to be an independent significant risk factor for asthma (OR=3.37; 95% CI=1.76-6.46; p<0.001). In addition, many other risk factors were found to be significant predictors of asthma, including bottlefeeding (OR=27.29; 95% CI=13.54-54.99; p<0.001) and low birth weight (OR=16.7; 95% CI=6.97-37.49; p<0.001).
Conclusion:
Caesarean section is significantly associated with an increased risk of childhood asthma.
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