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Published on: April 11, 2019
Assessing pupil reaction to light using ultrasound in a sick neonate with Hypoxic Ischemic Encephalopathy
1Department of Pediatrics, Section of Neonatology, University of Calgary, AB, Canada.
Insights
Point-of-care ultrasound offers a novel method to assess pupillary light response in infants with hypoxic ischemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). This technique aids neurological assessment and prognostication in critically ill neonates.
Area of Science:
- Neonatal neurology
- Pediatric critical care
- Medical imaging technology
Background:
- Pupillary light response is crucial for neurological assessment in infants with hypoxic ischemic encephalopathy (HIE).
- Assessing pupil reactivity can be difficult in critically ill neonates due to generalized edema.
- Therapeutic hypothermia (TH) eligibility and prognostication rely on serial neurological evaluations.
Purpose of the Study:
- To introduce a simple, bedside point-of-care ultrasound (POCUS) technique for evaluating pupillary light response.
- To demonstrate the utility of POCUS in neonates with HIE undergoing TH.
- To address the challenges of traditional pupillary examination in edematous infants.
Main Methods:
- A case report detailing the application of bedside POCUS for pupil examination.
- Utilized POCUS to visualize and assess the pupillary light reflex in a neonate.
- Focused on a patient with moderate HIE receiving TH.
Main Results:
- Successfully demonstrated pupillary light response using POCUS in an infant with HIE and edema.
- The technique provided a feasible alternative to traditional methods.
- Facilitated ongoing neurological assessment during TH.
Conclusions:
- Bedside POCUS is a viable and simple method for assessing pupillary light response in infants with HIE.
- This technique can overcome challenges posed by edema in critically ill neonates.
- POCUS can aid in prognostication and management decisions for infants undergoing TH.
Abstract:
Examining pupil reaction to light is an important component of the neurological examination in infants with hypoxic ischemic encephalopathy (HIE) to determine eligibility for therapeutic hypothermia (TH) and as part of serial neurological assessment for prognostication. Pupil examination can be challenging in critically ill infants with generalized edema. In this paper I report a simple technique using bedside point of care ultrasound to examine the pupil reaction to light in an infant with moderate HIE undergoing therapeutic hypothermia.

