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Hippocampal Neuronal Cultures to Detect and Study New Pathogenic Antibodies Involved in Autoimmune Encephalitis

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Double Pathology in Rasmussen Encephalitis.

Iga A Fudyma¹, Nitin R Wadhwani²

¹Midwestern University, Downers Grove, IL.

Pediatric Neurology Briefs

|March 18, 2020

Summary

This summary is machine-generated.

This study reviewed Rasmussen Encephalitis (RE) cases undergoing surgery and pathology evaluation. It determined the frequency of double pathology in these rare neurological disorder cases.

Keywords:

Double Pathology Epilepsy Rasmussen Encephalitis

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Area of Science:

Neurology
Pathology
Pediatric Medicine

Background:

Rasmussen Encephalitis (RE) is a rare, chronic inflammatory neurological disease affecting one cerebral hemisphere.
Surgical intervention and pathological evaluation are crucial for diagnosing and understanding RE.
The presence of 'double pathology' in RE cases requires further investigation.

Purpose of the Study:

To determine the frequency of double pathology in patients with Rasmussen Encephalitis.
To analyze surgical and pathological findings in RE cases.

Main Methods:

Retrospective review of electronic medical records.
Identification of all Rasmussen Encephalitis cases undergoing surgery with pathological evaluation.
Study period: 2005-2019 at Children's Hospital Colorado.

Main Results:

The frequency of double pathology in surgically treated Rasmussen Encephalitis cases was determined.
Specific pathological findings associated with double pathology were identified.

Conclusions:

The study provides data on the occurrence of double pathology in Rasmussen Encephalitis.
Findings contribute to the understanding of the histopathological spectrum of RE.