Related Experiment Video
Updated: Dec 26, 2025

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
[Study considering the use of medicines in children receiving free care]
Boukary Sana1,2, Ahmed Kaboré2, Hervé Hien3,4
1Direction Générale de l'Accès aux Produits de Santé, Ouagadougou, Burkina Faso.
Insights
Rational medicine use in children under five is a concern in Africa. This study found irrational prescribing, particularly with antibiotics, highlighting the need for better pediatric care to prevent overuse and antibiotic resistance.
Area of Science:
- Pediatric Pharmacology
- Global Health
- Health Systems Research
Background:
- Rational medical prescription is a critical issue for African health systems.
- This study focuses on medicine use in children aged 0-5 years receiving free healthcare.
Purpose of the Study:
- To analyze medicine utilization patterns in young children (0-5 years) under a free care program.
- To identify potential areas of irrational prescribing in pediatric populations.
Main Methods:
- A cross-sectional study was conducted in 20 randomly selected primary health facilities in Ouagadougou.
- Data analysis utilized World Health Organization/International Network for the Rational Use of Drugs (WHO/INRUD) guidelines.
- Descriptive statistics (average, standard deviation) and ANOVA tests were employed.
Main Results:
- 1,206 prescriptions were analyzed between April 2016 and March 2017.
- The average number of medicines per prescription was 2.9, with 88.7% being generic.
- 83.2% of consultations involved antibiotic prescriptions, and 9.3% included injectables.
Conclusions:
- Irrational prescribing, especially concerning antibiotics, was identified as a major issue.
- Urgent attention is needed for the treatment of children under five to curb excessive medicine consumption.
- Preventing overuse is crucial to combat the growing threat of antibiotic resistance.
Introduction:
Rational medical prescription is a concern for the health systems and policies of African countries. The purpose of this study was to analyze the use of medicines in children aged 0 to 5 years receiving free care.
Methods:
We conducted a cross-sectional study considering the use of medicines in 20 randomly selected health facilities level 1 in Ouagadougou. The reference of the World Health Organization and of the International Network for the Rational Use of Drugs (WHO/INRUD) was used to analyze data. Descriptive statistics were used as the average and standard deviation. Differences were measured using ANOVA test.
Results:
In total, 1.206 prescriptions were reviewed between April 2016 and March 2017. The number of medicines issued on prescription was 2.9, the percentage of generic medicines prescribed was 88.7% and 97.7% of medicines prescribed were registered on the National List of Essential Medicines. The percentage of consultations during which antibiotics were prescribed was 83.2%, and 9.3% of prescriptions contained at least one injectable product.
Conclusion:
Irrational prescription is mainly relates to the use of antibiotics. Essential alertness should be given to the treatment of children less than 5 years to avoid an excessive consumption of medicines and the emergence of antibiotic resistance.
More Related Videos
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Drug Dosing: Infants and Children
Factors Affecting Drug Response: Overview
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Distribution

