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Related Experiment Video

Updated: Dec 26, 2025

In Vitro Canine Neutrophil Extracellular Trap Formation: Dynamic and Quantitative Analysis by Fluorescence Microscopy

In Vitro Canine Neutrophil Extracellular Trap Formation: Dynamic and Quantitative Analysis by Fluorescence Microscopy

Published on: August 24, 2018

Trapped Neutrophil Syndrome in a Border Collie.

Ashley K Hegler¹, Amy M Grooters¹, Shannon D Dehghanpir¹

¹From Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana.

Journal of the American Animal Hospital Association

|March 18, 2020

Summary

A genetic mutation caused trapped neutrophil syndrome (TNS) in a Border Collie, leading to severe joint inflammation and diarrhea. Prednisone treatment provided rapid improvement, highlighting its therapeutic potential.

Area of Science:

Veterinary Medicine
Canine Genetics
Immunology

Background:

Trapped neutrophil syndrome (TNS) is a rare canine disorder.
It is characterized by severe inflammation and affects young dogs.

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