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The Association between Hypertension and Race/Ethnicity among Breast Cancer Survivors

Michelle S Williams1,2, Bettina M Beech3,4, Derek M Griffith4,5

  • 1Department of Population Health Science, John D. Bower School of Population Health, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS, 39216, USA. mwilliams16@umc.edu.

Journal of Racial and Ethnic Health Disparities
|March 19, 2020
PubMed

Insights

African American breast cancer survivors have a 30% higher prevalence of hypertension compared to White survivors. This increased risk of hypertension contributes to a higher risk of cardiovascular disease (CVD) in this population.

Area of Science:

  • Cardiology
  • Oncology
  • Public Health

Background:

  • Hypertension is a major modifiable risk factor for cardiovascular disease (CVD).
  • African American women with early-stage breast cancer face a higher risk of premature CVD-related death.
  • Understanding hypertension prevalence in breast cancer survivors is crucial for targeted interventions.

Purpose of the Study:

  • To investigate the association between hypertension and race/ethnicity in breast cancer survivors.
  • To analyze hypertension prevalence among African American and White breast cancer survivors.
  • To utilize data from the National Health and Nutrition Examination Surveys (NHANES) for this analysis.

Main Methods:

  • Identified Non-Hispanic African American and Non-Hispanic White women diagnosed with breast cancer.
  • Defined hypertension based on medication use, systolic blood pressure (≥140 mmHg), or diastolic blood pressure (≥90 mmHg).
  • Employed modified Poisson regression to estimate prevalence ratios (PR) and 95% confidence intervals (CI), controlling for confounders.

Main Results:

  • The study included 524 breast cancer survivors: 107 (20.4%) African American and 417 (80.0%) White.
  • Adjusted analysis revealed African American survivors had a 30% higher prevalence of hypertension (PR=1.30 [95% CI, 1.11-1.52]) than White survivors.
  • This association persisted after controlling for age, socioeconomic factors, lifestyle, obesity, and diabetes.

Conclusions:

  • African American breast cancer survivors exhibit a significantly higher prevalence of hypertension.
  • This elevated hypertension risk contributes to an increased likelihood of cardiovascular disease (CVD) in this demographic.
  • Findings underscore the need for proactive hypertension management in African American breast cancer survivors to mitigate CVD risk.
Abstract

Keywords:
Breast cancer survivorHealth disparitiesHypertension

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