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[Rise and threat of infectious diseases].
W J Wiersinga1,2, M P G Koopmans3, J T van Dissel4
1Amsterdam UMC, afd. Inwendige Geneeskunde, onderafd. Infectieziekten en Center forExperimentalMolecularMedicine (CEMM), Amsterdam.
Nederlands Tijdschrift Voor Geneeskunde
|March 19, 2020
Summary
Infectious diseases, including HIV, malaria, tuberculosis, and sepsis, cause a significant global burden. Emerging threats from antimicrobial resistance and climate change necessitate preparedness for both new and old infectious diseases.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- Infectious diseases caused 25% of global deaths in 2019, with significant burden in the Netherlands.
- Factors like aging populations, vaccine hesitancy, immunosuppression, and globalization exacerbate infectious disease risks.
- Climate change and pathogen adaptability, including antimicrobial resistance, pose increasing threats.
Purpose of the Study:
- To analyze the current and future threats posed by infectious diseases.
- To understand the drivers behind the emergence of new infectious diseases.
- To inform strategies for managing infectious disease risks.
Main Methods:
- Review of global and national infectious disease statistics.
- Analysis of contributing factors to disease burden and emergence.
- Examination of pathogen adaptation and resistance trends.
Main Results:
- Infectious diseases remain a major cause of mortality worldwide and in the Netherlands.
- Multiple societal and environmental factors are increasing vulnerability to infections.
- Pathogen evolution, particularly antimicrobial resistance, presents a critical challenge.
Conclusions:
- Proactive strategies are essential to address both established and emerging infectious disease threats.
- Understanding historical patterns is crucial for predicting and mitigating future outbreaks.
- Integrated approaches are needed to combat the complex challenges of infectious diseases.
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